Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.40 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.40 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.40 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | GGT1 | P19440 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7140684 | 0.99 | CYP4A11 (0.43) | CYP4A11ATML3MBTL1ALDH1A1CYP1A2 | |
| SCHEMBL8208855 | 0.87 | GGT1 (0.53) | L3MBTL1ALDH1A1CYP2C9CYP2C19GGT1 | |
| SCHEMBL8210953 | 0.87 | GGT1 (0.53) | L3MBTL1ALDH1A1CYP2C9CYP2C19GGT1 | |
| Hydrochloric Acid SCHEMBL27506820 | 0.86 | GGT1 (0.52) | L3MBTL1ALDH1A1CYP2C9CYP2C19GGT1 | |
| Hydrochloric Acid SCHEMBL8208849 | 0.86 | GGT1 (0.52) | L3MBTL1ALDH1A1CYP2C9CYP2C19GGT1 | |
| SCHEMBL8638780 | 0.85 | GGT1 (0.51) | CYP4A11ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7144558 | 0.83 | SIGMAR1 (0.50) | L3MBTL1ALDH1A1CYP2C9CYP2C19GGT1 | |
| Hydrochloric Acid SCHEMBL7146346 | 0.83 | ALDH1A1 (0.41) | CYP4A11ALDH1A1CYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL7144556 | 0.82 | SIGMAR1 (0.49) | L3MBTL1ALDH1A1CYP2C9CYP2C19GGT1 | |
| Hydrochloric Acid SCHEMBL7144561 | 0.82 | SIGMAR1 (0.49) | L3MBTL1ALDH1A1CYP2C9CYP2C19GGT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951465-B1 | ALPHA-AMINO ACID AMIDES, PREPARATION THEREOF AND THE THERAPEUTICAL USE THEREOF | CHIESI FARMA SPA (IT) | 2003-04-16 | — | — | EP | disclosed |
| US-6114391-A | A DERIVATIVES OF SERINAMIDE, GLYCINAMIDE, ALANINAMIDE AND PHENYLALANINAMIDE FOR TREATING NEUROLOGICAL DISEASES | CHIESI FARMACEUTICI S.P.A. (IT) | 2000-09-05 | — | — | US | disclosed |