Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GGT1 | P19440 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7144556 | 0.99 | SIGMAR1 (0.49) | SIGMAR1ALDH1A1CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL7144561 | 0.99 | SIGMAR1 (0.49) | SIGMAR1ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL8210953 | 0.96 | GGT1 (0.53) | SIGMAR1ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL8208855 | 0.96 | GGT1 (0.53) | SIGMAR1ALDH1A1CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL27506820 | 0.94 | GGT1 (0.52) | SIGMAR1ALDH1A1CYP2C9CYP2C19KMT2A | |
| Hydrochloric Acid SCHEMBL8208849 | 0.94 | GGT1 (0.52) | SIGMAR1ALDH1A1CYP2C9CYP2C19KMT2A | |
| SCHEMBL7452621 | 0.87 | SIGMAR1 (0.58) | SIGMAR1ALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL4561048 | 0.84 | GGT1 (0.51) | SIGMAR1CYP2C9CYP2C19KMT2AHPGD | |
| SCHEMBL7140689 | 0.83 | CYP4A11 (0.44) | ALDH1A1CYP2C9CYP2C19KMT2AGGT1 | |
| Hydrocinnamyl Alcohol SCHEMBL28255231 | 0.82 | POLB (0.54) | SIGMAR1ALDH1A1CYP2C9CYP2C19HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951465-B1 | ALPHA-AMINO ACID AMIDES, PREPARATION THEREOF AND THE THERAPEUTICAL USE THEREOF | CHIESI FARMA SPA (IT) | 2003-04-16 | — | — | EP | disclosed |
| US-6114391-A | A DERIVATIVES OF SERINAMIDE, GLYCINAMIDE, ALANINAMIDE AND PHENYLALANINAMIDE FOR TREATING NEUROLOGICAL DISEASES | CHIESI FARMACEUTICI S.P.A. (IT) | 2000-09-05 | — | — | US | disclosed |