Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | CDKN1A | P38936 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.51 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.49 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | JAK1 | P23458 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.48 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6870164 | 0.93 | KDM4E (0.58) | MAPTKDM4ECDKN1ATDP1NPC1 | |
| SCHEMBL7039193 | 0.91 | LMNA (0.61) | MAPTKDM4EALDH1A1TDP1NPC1 | |
| SCHEMBL7042283 | 0.91 | MAPT (0.56) | MAPTKDM4ECDKN1AADORA2AADORA1 | |
| SCHEMBL7149099 | 0.90 | KDM4E (0.55) | MAPTKDM4ECDKN1AALDH1A1NPC1 | |
| SCHEMBL7148767 | 0.89 | KDM4E (0.54) | MAPTKDM4ETDP1NPC1RAB9A | |
| SCHEMBL7149095 | 0.89 | MAPT (0.54) | MAPTKDM4EADORA2AADORA1ALDH1A1 | |
| SCHEMBL7143995 | 0.84 | ADORA1 (0.53) | MAPTKDM4EADORA2AADORA1ALDH1A1 | |
| SCHEMBL7045952 | 0.84 | TDP2 (0.52) | MAPTKDM4EALDH1A1TDP1NPC1 | |
| SCHEMBL7146666 | 0.84 | ALDH1A1 (0.53) | MAPTKDM4ECDKN1AALDH1A1TDP1 | |
| SCHEMBL7146900 | 0.84 | PDE4D (0.50) | MAPTKDM4ETDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514989-B1 | Has a good affinity to the adenosine receptor and can therefore be used for the treatment or protection of diseases mediated by this receptor | HOFFMANN-LA ROCHE INC. | 2003-02-04 | — | — | US | disclosed |
| US-6514989-B1 | Has a good affinity to the adenosine receptor and can therefore be used for the treatment or protection of diseases mediated by this receptor | HOFFMANN-LA ROCHE INC. | 2003-02-04 | — | — | US | disclosed |
| US-6514989-B1 | Has a good affinity to the adenosine receptor and can therefore be used for the treatment or protection of diseases mediated by this receptor | HOFFMANN-LA ROCHE INC. | 2003-02-04 | — | — | US | disclosed |