Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNJ11 | Q14654 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6611475 | 0.89 | KCNJ11 (0.43) | KCNJ11GAAKMT2AMEN1RAB9A | |
| SCHEMBL6611355 | 0.89 | KCNJ11 (0.42) | KCNJ11GAAKMT2AMEN1RAB9A | |
| SCHEMBL6613974 | 0.83 | NPC1 (0.39) | KCNJ11RAB9AALDH1A1P2RX7NPC1 | |
| SCHEMBL6612739 | 0.83 | LMNA (0.49) | KCNJ11GAAKMT2AMEN1RAB9A | |
| SCHEMBL6611989 | 0.83 | SLC6A9 (0.41) | KCNJ11KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL6611088 | 0.83 | KCNJ11 (0.46) | KCNJ11GAAKMT2AMEN1RAB9A | |
| SCHEMBL7742482 | 0.82 | MEN1 (0.52) | KCNJ11GAAKMT2AMEN1RAB9A | |
| SCHEMBL6640615 | 0.82 | KCNJ11 (0.45) | KCNJ11GAAKMT2AMEN1RAB9A | |
| SCHEMBL7736656 | 0.81 | POLB (0.43) | KCNJ11KMT2AMEN1RAB9ASMN1; SMN2 | |
| SCHEMBL6642968 | 0.80 | MEN1 (0.44) | KCNJ11KMT2AMEN1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003506355-A | — | — | 2003-02-18 | — | — | JP | claimed |
| EP-1198456-A2 | POTASSIUM CHANNEL OPENERS | Abbott Laboratories (US) | 2002-04-24 | — | — | EP | claimed |
| WO-2001009096-A2 | POTASSIUM CHANNEL OPENERS | ABBOTT LABORATORIES (US) | 2001-02-08 | — | — | WO | claimed |