Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 5/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 5/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7145177 | 0.90 | MAPT (0.43) | MTNR1AMTNR1BKMT2APOLBCYP2C9 | |
| SCHEMBL8666726 | 0.90 | MAPT (0.43) | MTNR1AMTNR1BKMT2APOLBCYP2C9 | |
| SCHEMBL7137161 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BMAOAMAOBKMT2A | |
| SCHEMBL7137157 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BMAOAMAOBKMT2A | |
| SCHEMBL7137160 | 0.84 | MTNR1A (0.51) | MTNR1AMTNR1BMAOAMAOBKMT2A | |
| Hydrochloric Acid SCHEMBL7145984 | 0.83 | MTNR1A (0.50) | MTNR1AMTNR1BMAOAMAOBTP53 | |
| SCHEMBL2980372 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BMAOAMAOBKMT2A | |
| SCHEMBL4738196 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BMAOAMAOBKMT2A | |
| SCHEMBL2822394 | 0.76 | MTNR1A (0.56) | MTNR1AMTNR1BMAOAMAOBKMT2A | |
| SCHEMBL7029994 | 0.75 | MTNR1A (0.54) | MTNR1AMTNR1BMAOAMAOBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0951465-B1 | ALPHA-AMINO ACID AMIDES, PREPARATION THEREOF AND THE THERAPEUTICAL USE THEREOF | CHIESI FARMA SPA (IT) | 2003-04-16 | — | — | EP | disclosed |
| US-6114391-A | A DERIVATIVES OF SERINAMIDE, GLYCINAMIDE, ALANINAMIDE AND PHENYLALANINAMIDE FOR TREATING NEUROLOGICAL DISEASES | CHIESI FARMACEUTICI S.P.A. (IT) | 2000-09-05 | — | — | US | disclosed |