Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7140571 | 0.78 | EHMT2 (0.40) | ALDH1A1TP53TDP1MEN1ESR1 | |
| SCHEMBL7141187 | 0.74 | KMT2A (0.44) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL31515627 | 0.69 | KMT2A (0.49) | ALDH1A1TP53TDP1MEN1ESR1 | |
| SCHEMBL9803 | 0.69 | KMT2A (0.49) | ALDH1A1TP53TDP1MEN1ESR1 | |
| SCHEMBL7459870 | 0.69 | NAMPT (0.56) | ALDH1A1TP53TDP1GAAHTT | |
| SCHEMBL260819 | 0.68 | MEN1 (0.47) | ALDH1A1TP53TDP1MEN1ESR1 | |
| SCHEMBL31244372 | 0.68 | MEN1 (0.47) | ALDH1A1TP53TDP1MEN1ESR1 | |
| SCHEMBL8019502 | 0.68 | KMT2A (0.47) | ALDH1A1TP53TDP1MEN1ESR1 | |
| SCHEMBL10640718 | 0.67 | KMT2A (0.44) | ALDH1A1TP53TDP1MEN1ESR1 | |
| SCHEMBL1055254 | 0.67 | KMT2A (0.44) | ALDH1A1TP53TDP1MEN1ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1086124-B1 | NOVEL CYCLOSPORINS | CHEM AG C (CH) | 2003-11-19 | — | — | EP | disclosed |
| US-6583265-B1 | Compound for use in the prevention of viral and bacterial infections | C-CHEM AG (CH) | 2003-06-24 | — | — | US | disclosed |
| EP-1086124-A1 | NOVEL CYCLOSPORINS | C-Chem AG (CH) | 2001-03-28 | — | — | EP | disclosed |
| WO-1999065933-A1 | NOVEL CYCLOSPORINS | C-CHEM AG (CH) | 1999-12-23 | — | — | WO | disclosed |