Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149546 | 0.75 | HRH3 (0.32) | DHFR | |
| SCHEMBL4621770 | 0.65 | DHFR (0.43) | DHFR | |
| SCHEMBL6032201 | 0.65 | DHFR (0.39) | DHFR | |
| SCHEMBL3921677 | 0.65 | — | — | |
| SCHEMBL3921483 | 0.62 | ALDH1A1 (0.30) | — | |
| SCHEMBL27875517 | 0.61 | DHFR (0.44) | DHFR | |
| SCHEMBL11637078 | 0.61 | ACHE (0.33) | — | |
| SCHEMBL27491660 | 0.60 | DHFR (0.33) | DHFR | |
| SCHEMBL27557336 | 0.60 | ELANE (0.35) | DHFR | |
| SCHEMBL4985361 | 0.60 | DHFR (0.41) | DHFRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343827-A1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, THEIR CORRESPONDING N-OXIDES AND CONTROLLED RADICAL POLYMERIZATION THEREWITH | Ciba SC Holding AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048205-A1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, THEIR CORRESPONDING N-OXIDES AND CONTROLLED RADICAL POLYMERIZATION THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |