Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4980736 | 0.76 | OPRM1 (0.32) | OPRM1OPRD1OPRK1 | |
| SCHEMBL7142047 | 0.75 | DHFR (0.31) | DHFR | |
| SCHEMBL4985897 | 0.67 | — | — | |
| SCHEMBL6032201 | 0.67 | DHFR (0.39) | DHFR | |
| SCHEMBL4621770 | 0.61 | DHFR (0.43) | HRH3SIGMAR1DHFR | |
| SCHEMBL9621057 | 0.59 | SIGMAR1 (0.48) | SIGMAR1OPRM1 | |
| SCHEMBL144042 | 0.59 | ALDH1A1 (0.54) | HRH3SIGMAR1 | |
| SCHEMBL6435277 | 0.59 | MEN1 (0.42) | DHFR | |
| SCHEMBL28674344 | 0.58 | MMP1 (0.38) | SIGMAR1OPRM1OPRD1OPRK1 | |
| SCHEMBL21598302 | 0.58 | ALDH1A1 (0.53) | HRH3SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343827-A1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, THEIR CORRESPONDING N-OXIDES AND CONTROLLED RADICAL POLYMERIZATION THEREWITH | Ciba SC Holding AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002048205-A1 | N-ALKOXY-4,4-DIOXY-POLYALKYL-PIPERIDINE COMPOUNDS, THEIR CORRESPONDING N-OXIDES AND CONTROLLED RADICAL POLYMERIZATION THEREWITH | CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) | 2002-06-20 | — | — | WO | disclosed |