SCHEMBL7142332

SCHEMBL7142332

O=C1NCCCCC1Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.57

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.57
GAA P10253 2/20 0.57
LMNA P02545 1/20 0.57
POLB P06746 1/20 0.57
EPHX1 P07099 1/20 0.43
ALDH1A1 P00352 5/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
NAMPT P43490 1/20 0.41
RAB9A P51151 3/20 0.41
CCR2 P41597 3/20 0.40
KDM4E B2RXH2 2/20 0.40
SLC6A3 Q01959 1/20 0.39
RECQL P46063 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5567663 0.80 ALDH1A1 (0.50) MAPTGAALMNAPOLBEPHX1
SCHEMBL7150634 0.80 DDB1 (0.57) ALDH1A1RAB9ACCR2KDM4ENPC1
SCHEMBL18415603 0.80 RAB9A (0.62) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL20194435 0.80 RAB9A (0.62) MAPTGAAALDH1A1SMN1; SMN2RAB9A
Hydrochloric Acid SCHEMBL7150025 0.78 DDB1 (0.56) ALDH1A1RAB9ACCR2KDM4ENPC1
SCHEMBL31730212 0.77 ALDH1A1 (0.42) MAPTGAALMNAPOLBALDH1A1
SCHEMBL8656203 0.76 CRBN (0.65) MAPTGAALMNAPOLB
SCHEMBL29346389 0.76 ALDH1A1 (0.44) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL31730159 0.76 ALDH1A1 (0.44) MAPTGAAALDH1A1SMN1; SMN2RAB9A
SCHEMBL31730148 0.75 LMNA (0.43) MAPTGAALMNAPOLBEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR MITSUBISHI TANABE PHARMA CORPORATION (JP) 2025-12-25 US disclosed
EP-4650348-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR Mitsubishi Tanabe Pharma Corporation (JP) 2025-11-19 EP disclosed
US-6630004-B1 Ready-to-use dyeing composition for keratinous fibers comprising, in dyeing medium, oxidizing agent chosen from hydrogen peroxide, urea hydrogen peroxide, alkali metal bromates, persalts and enzymes, and specified oxidation base L'OREAL S.A. (FR) 2003-10-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250388593-A1 CEREBLON E3 LIGASE BINDING COMPOUND, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND PRODUCTION METHOD THEREFOR CRBN, CUL1, CBL MAPT 2668/4885GAA 3378/4885LMNA 3163/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.