Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | F12 | P00748 | 1/20 | 0.53 |
| ▸ | NCF1 | P14598 | 1/20 | 0.53 |
| ▸ | NOS3 | P29474 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.53 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | BACE1 | P56817 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358060 | 0.82 | — | — | |
| SCHEMBL33700 | 0.82 | — | — | |
| SCHEMBL4870156 | 0.82 | NOS3 (0.52) | NOS3NOS1NOS2BACE1TSHR | |
| Hydrochloric Acid SCHEMBL11635965 | 0.80 | — | — | |
| Methane SCHEMBL28430816 | 0.80 | — | — | |
| 1-Naphthol SCHEMBL27401651 | 0.80 | ALDH1A1 (0.63) | CYP1A2TSHRMMP2CHRM1COMT | |
| SCHEMBL6029051 | 0.79 | MMP2 (0.48) | PLAUF12NCF1NOS3NOS1 | |
| 1-Naphthol SCHEMBL27383157 | 0.79 | ALDH1A1 (0.61) | CYP1A2TSHRMMP2CHRM1COMT | |
| 1-Naphthol SCHEMBL28823427 | 0.79 | ALDH1A1 (0.61) | CYP1A2TSHRMMP2CHRM1COMT | |
| 1-Naphthol SCHEMBL11061218 | 0.78 | CYP1A2 (0.90) | CYP1A2PLAUTSHRKDM4EMAPKAPK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267810-A2 | METHOD FOR COLOURING HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001076546-A2 | METHOD FOR COLOURING HAIR | THE PROCTER & GAMBLE COMPANY (US) | 2001-10-18 | — | — | WO | disclosed |