Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 2/20 | 0.52 |
| ▸ | NOS1 | P29475 | 2/20 | 0.52 |
| ▸ | NOS2 | P35228 | 2/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MMP2 | P08253 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | COMT | P21964 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29358060 | 1.00 | — | — | |
| SCHEMBL33700 | 1.00 | — | — | |
| Methane SCHEMBL28430816 | 0.97 | — | — | |
| Hydrochloric Acid SCHEMBL11635965 | 0.97 | — | — | |
| Sulfuric Acid SCHEMBL1712803 | 0.89 | KDM4E (0.56) | NOS3NOS1NOS2NAPRTALDH1A1 | |
| SCHEMBL6029051 | 0.87 | MMP2 (0.48) | NOS3NOS1NOS2NAPRTALDH1A1 | |
| 1-Naphthol SCHEMBL7142810 | 0.82 | CYP1A2 (0.61) | NOS3NOS1NOS2ALDH1A1TSHR | |
| SCHEMBL16196249 | 0.80 | MKNK1 (0.47) | NOS3NOS1NOS2NAPRTALDH1A1 | |
| SCHEMBL3272057 | 0.78 | NOS3 (0.47) | NOS3NOS1NOS2ALDH1A1TSHR | |
| SCHEMBL3265555 | 0.78 | PRKCI (0.44) | NOS3NOS1NOS2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7431742-B2 | Hair coloring kits and methods of use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2008-10-07 | — | — | US | disclosed |
| US-20070251025-A1 | Hair coloring kits and methods of use thereof | THE PROCTER & GAMBLE COMPANY | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070251025-A1 | Hair coloring kits and methods of use thereof | COXFA4L2, SQOR, GPX4 | NOS3 600/4885NOS1 875/4885NOS2 744/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.