Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142985 | 1.00 | HRH3 (0.33) | HRH3FFAR4PTGER4TBXA2R | |
| SCHEMBL6747271 | 0.79 | ITGB3 (0.34) | HRH3 | |
| SCHEMBL6749057 | 0.75 | HSD11B1 (0.44) | — | |
| SCHEMBL6745649 | 0.74 | CPB1 (0.31) | — | |
| SCHEMBL6745650 | 0.74 | CPB1 (0.31) | — | |
| SCHEMBL6747404 | 0.73 | — | — | |
| SCHEMBL6747400 | 0.73 | — | — | |
| Oxalic Acid SCHEMBL7148808 | 0.72 | HSD11B1 (0.41) | — | |
| SCHEMBL6747648 | 0.71 | BRD4 (0.32) | — | |
| SCHEMBL8324814 | 0.68 | CHRM1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |