Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACSS2 | Q9NR19 | 3/20 | 0.34 |
| ▸ | THRB | P10828 | 2/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5835355 | 1.00 | ACSS2 (0.34) | ACSS2THRBESR2CYP1A2CYP2C9 | |
| SCHEMBL29353940 | 0.97 | ACSS2 (0.35) | ACSS2ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL768935 | 0.97 | ACSS2 (0.35) | ACSS2ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL7143972 | 0.93 | ACSS2 (0.34) | ACSS2 | |
| SCHEMBL5835358 | 0.93 | ACSS2 (0.34) | ACSS2 | |
| SCHEMBL2639249 | 0.93 | ACSS2 (0.35) | ACSS2THRBESR2CYP1A2CYP2C9 | |
| SCHEMBL2638123 | 0.92 | THRB (0.33) | THRB | |
| SCHEMBL768936 | 0.91 | ACSS2 (0.34) | ACSS2ESR2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5835161 | 0.90 | ACSS2 (0.40) | ACSS2CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2638115 | 0.90 | ACSS2 (0.36) | ACSS2ESR2CYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515051-B2 | Stability and durability and a low loss rate when incorporated into automotive coatings; soluble in a variety of substrates including thermoplastic polymers and often are colorless | CIBA SPECIALTY CHEMICALS CORPORATION | 2003-02-04 | — | — | US | disclosed |
| US-6458872-B1 | FOR USE IN AUTOMOTIVE COATINGS, THERMOPLASTIC FORMULATIONS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-10-01 | — | — | US | disclosed |
| US-20020099221-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-07-25 | — | — | US | disclosed |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2002-05-30 | — | — | US | disclosed |
| US-6262151-B1 | FOR AUTOMOTIVE COATINGS | CIBA SPECIALTY CHEMICALS CORPORATION | 2001-07-17 | — | — | US | disclosed |
| US-20010007886-A1 | Benzotriazole UV absorbers having enhanced durability | RAVICHANDRAN RAMANATHAN (US) | 2001-07-12 | — | — | US | disclosed |
| US-6166218-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-12-26 | — | — | US | disclosed |
| US-5977219-A | Benzotriazole UV absorbers having enhanced durability | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 1999-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020099221-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | ACSS2 2706/4885THRB 800/4885ESR2 557/4885 |
| US-20020065341-A1 | Benzotriazole UV absorbers having enhanced durability | TERT, AHR, ARNT | ACSS2 2706/4885THRB 800/4885ESR2 557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.