Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | DHFR | P00374 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CTSC | P53634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004971 | 0.84 | ELANE (0.38) | ELANECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL11544340 | 0.73 | CYP3A4 (0.44) | ELANECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL11406016 | 0.70 | CYP3A4 (0.46) | ELANECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL11156260 | 0.70 | CYP3A4 (0.41) | ELANECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL5861689 | 0.69 | KDM4E (0.42) | CYP2D6CYP2C19TSHRCYP2C9ALDH1A1 | |
| SCHEMBL11546126 | 0.69 | SLC6A3 (0.43) | ELANECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL3726266 | 0.69 | CTSC (0.50) | ELANECYP3A4CYP2D6CYP1A2CYP2C19 | |
| SCHEMBL2478803 | 0.69 | CTSC (0.50) | ELANECYP3A4CYP2D6CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL5861812 | 0.69 | ALDH1A1 (0.41) | CYP2D6CYP2C19TSHRCYP2C9ALDH1A1 | |
| SCHEMBL498386 | 0.69 | CTSC (0.50) | ELANECYP3A4CYP2D6CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112071-A4 | GROWTH HORMONE SECRETAGOGUES | LILLY CO ELI (US) | 2003-03-19 | — | — | EP | disclosed |
| EP-1112071-A1 | GROWTH HORMONE SECRETAGOGUES | Eli Lilly & Company (US) | 2001-07-04 | — | — | EP | disclosed |
| WO-2000010565-A1 | GROWTH HORMONE SECRETAGOGUES | ELI LILLY AND COMPANY (US) | 2000-03-02 | — | — | WO | disclosed |