Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA9 | Q16790 | 4/20 | 0.39 |
| ▸ | F2 | P00734 | 6/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.35 |
| ▸ | ACP1 | P24666 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144517 | 0.76 | MAPT (0.47) | MAPTALDH1A1CA12CA2CA9 | |
| Sulfuric Acid SCHEMBL8501572 | 0.75 | ALDH1A1 (0.42) | MAPTALDH1A1CA12CA2CA9 | |
| Sulfuric Acid SCHEMBL2484445 | 0.73 | ALDH1A1 (0.52) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL8894563 | 0.73 | MAPT (0.47) | MAPTALDH1A1L3MBTL1KDM4ECYP3A4 | |
| Sulfuric Acid SCHEMBL8501318 | 0.72 | CA12 (0.47) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL2183092 | 0.71 | CA2 (0.59) | MAPTALDH1A1CA12CA2CA9 | |
| Sulfuric Acid SCHEMBL8441340 | 0.70 | ALDH1A1 (0.48) | MAPTALDH1A1CA12CA2CA9 | |
| Sulfuric Acid SCHEMBL1605645 | 0.70 | MAPT (0.59) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL8445072 | 0.70 | ALDH1A1 (0.53) | MAPTALDH1A1CA12CA2CA9 | |
| SCHEMBL1608002 | 0.70 | ALDH1A1 (0.52) | MAPTALDH1A1CA12CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5998117-A | METHINE DYE CAPABLE OF BEING DECOLORED BY REACTING WITH A COLOR DEVELOPING AGENT. | KONICA CORPORATION (JP) | 1999-12-07 | — | — | US | disclosed |
| US-4433046-A | Silver halide photographic material | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1984-02-21 | — | — | US | disclosed |