Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9067778 | 0.88 | CXCR3 (0.59) | CXCR3PDE10A | |
| SCHEMBL7639262 | 0.86 | PIK3CD (0.47) | CXCR3 | |
| SCHEMBL5156390 | 0.84 | CXCR3 (0.46) | CXCR3 | |
| SCHEMBL7141275 | 0.83 | HRH3 (0.58) | CXCR3 | |
| SCHEMBL450061 | 0.82 | CXCR3 (0.54) | CXCR3PDE10A | |
| SCHEMBL7699242 | 0.78 | CXCR3 (0.48) | CXCR3PDE10A | |
| SCHEMBL14317533 | 0.77 | CXCR3 (0.56) | CXCR3PDE10A | |
| SCHEMBL1484065 | 0.77 | CXCR3 (0.56) | CXCR3PDE10A | |
| SCHEMBL12463889 | 0.77 | PTGS2 (0.47) | CXCR3 | |
| SCHEMBL14621133 | 0.77 | CXCR3 (1.00) | CXCR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1743891-A1 | Heterocyclic compounds and methods for modulating CXCR3 function | ChemoCentryx Inc (US) | 2007-01-17 | — | — | EP | disclosed |
| EP-1343505-A1 | CXCR3 ANTAGONISTS | Tularik Inc. (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002083143-A1 | CXCR3 ANTAGONISTS | TULARIK INC. (US) | 2002-10-24 | — | — | WO | disclosed |