Acrylic Acid Ethyl Ester

Acrylic Acid Ethyl Ester

SCHEMBL7145276

C=CC(=O)OCC.CCOC(=O)CCN(CCc1ccc(OC)cc1)S(=O)(=O)c1ccc(OC)cc1

nearest known ligand 0.61

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Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BMP1 P13497 18/20 0.61
ALDH1A1 P00352 1/20 0.51
TAS2R14 Q9NYV8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7003476 0.93 BMP1 (0.69) BMP1ALDH1A1TAS2R14
SCHEMBL7001435 0.87 BMP1 (0.67) BMP1ALDH1A1TAS2R14
SCHEMBL7000836 0.82 BMP1 (0.69) BMP1ALDH1A1TAS2R14
Acrylic Acid Ethyl Ester SCHEMBL7145280 0.82 BMP1 (0.50) BMP1ALDH1A1TAS2R14
SCHEMBL7112761 0.82 BMP1 (0.72) BMP1ALDH1A1TAS2R14
SCHEMBL7003868 0.78 ALDH1A1 (0.59) BMP1ALDH1A1TAS2R14
SCHEMBL7004788 0.78 BMP1 (0.66) BMP1ALDH1A1TAS2R14
SCHEMBL7005237 0.78 BMP1 (0.70) BMP1
SCHEMBL7093324 0.78 TP53 (0.65) BMP1ALDH1A1TAS2R14
Acrylic Acid Ethyl Ester SCHEMBL7003780 0.77 TAS2R14 (0.45) BMP1ALDH1A1TAS2R14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1154992-A4 N-SUBSTITUTED ARYLSULFONYLAMINO HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF C-PROTEINASE AND FOR TREATING OR PREVENTING DISORDERS RELATED TO UNREGULATED COLLAGEN PRODUCTION FIBROGEN INC (US) 2003-05-28 EP disclosed
EP-1154992-A1 N-SUBSTITUTED ARYLSULFONYLAMINO HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF C-PROTEINASE AND FOR TREATING OR PREVENTING DISORDERS RELATED TO UNREGULATED COLLAGEN PRODUCTION FIBROGEN, INC. (US) 2001-11-21 EP disclosed
WO-2000050390-A1 N-SUBSTITUTED ARYLSULFONYLAMINO HYDROXAMIC ACIDS USEFUL AS INHIBITORS OF C-PROTEINASE AND FOR TREATING OR PREVENTING DISORDERS RELATED TO UNREGULATED COLLAGEN PRODUCTION FIBROGEN, INC. (US) 2000-08-31 WO disclosed