Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11570799 | 0.87 | HPGD (0.50) | MCL1KMT2AMEN1POLBNPC1 | |
| SCHEMBL4540287 | 0.84 | RAB9A (0.56) | KMT2AMEN1NPC1SRD5A2ALDH1A1 | |
| SCHEMBL28157374 | 0.81 | NPC1 (0.56) | TAS2R14MAPK1MCL1KMT2AMEN1 | |
| SCHEMBL11570608 | 0.78 | ALDH1A1 (0.42) | NPC1ALDH1A1SMN1; SMN2MAPTHPGD | |
| Roxadimate SCHEMBL15518 | 0.78 | CA12 (0.53) | TP53TSHRKMT2AMEN1POLB | |
| Roxadimate SCHEMBL6851586 | 0.78 | CA12 (0.53) | TP53TSHRKMT2AMEN1POLB | |
| SCHEMBL338524 | 0.78 | POLB (0.44) | TP53TSHRPOLBALDH1A1SMN1; SMN2 | |
| Propylene Glycol SCHEMBL25433678 | 0.76 | NPC1 (0.59) | MAPK1TP53TSHRKMT2AMEN1 | |
| SCHEMBL64440 | 0.76 | MEN1 (0.56) | MAPK1TP53TSHRMCL1KMT2A | |
| SCHEMBL31010261 | 0.76 | TYR (0.40) | ALDH1A1SMN1; SMN2MAPTCRHBPCRHR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2662068-B1 | OIL-IN-WATER EMULSION COMPOSITION | KAO CORP (JP) | 2017-07-05 | — | — | EP | claimed |
| US-6620864-B2 | With a plasticizer, a catalyst for hardening by ring opening, a catalyst for hardening by light and as accelerator a p-aminobenzoic acid alkyl ester, N,N-disubstituted by hydroxyalkyl groups; free of contraction and adhesiveness | LSP DENTAL CHEMISTRY AG (CH) | 2003-09-16 | — | — | US | disclosed |