Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | STAT6 | P42226 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7151670 | 0.93 | LMNA (0.65) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7148438 | 0.92 | LMNA (0.64) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7144723 | 0.89 | LMNA (0.49) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7147603 | 0.88 | LMNA (0.57) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7149622 | 0.85 | ALDH1A1 (0.59) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7154156 | 0.85 | MAPT (0.48) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7150889 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7149883 | 0.83 | LMNA (0.53) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7150789 | 0.82 | MAPT (0.43) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 | |
| SCHEMBL7153854 | 0.82 | LMNA (0.52) | ALDH1A1HSD17B10LMNAMAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6642263-B2 | Antitumor agents, sulfided benzothiazole derivative containing sulfonamide | ICONIX PHARMACEUTICALS INC. | 2003-11-04 | — | — | US | disclosed |
| US-20030176474-A1 | Modulators of Rho C activity | ICONIX BIOSCIENCES, INC. | 2003-09-18 | — | — | US | disclosed |
| WO-2003043577-A2 | MODULATORS OF RHO C ACTIVITY | ICONIX PHARMACEUTICALS, INC. (US) | 2003-05-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030176474-A1 | Modulators of Rho C activity | RHOC, ARHGDIA, ROCK1 | ALDH1A1 2919/4885HSD17B10 2088/4885LMNA 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.