Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.51 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7043078 | 0.87 | JAK1 (0.60) | KDM4EALDH1A1HPGDGLAGAA | |
| SCHEMBL7144538 | 0.87 | PDE4D (0.49) | KDM4EALDH1A1HPGDHSD17B10TUBB4A | |
| SCHEMBL2257907 | 0.86 | MAPT (0.49) | KDM4EALDH1A1HPGDPDE4DJAK1 | |
| SCHEMBL2250839 | 0.86 | PDE4D (0.64) | KDM4EPDE4DJAK1PDE10A | |
| SCHEMBL7146570 | 0.84 | PDE4D (0.48) | NPC1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL7143153 | 0.84 | PDE4D (0.46) | KDM4EALDH1A1HPGDTUBB4ATUBB | |
| SCHEMBL7851265 | 0.79 | PDE10A (0.44) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6875680 | 0.78 | PDE10A (0.44) | NPC1RAB9ATUBB4ATUBBTUBA3C | |
| SCHEMBL7148123 | 0.78 | NUDT1 (0.55) | ALDH1A1HSD17B10NPC1TP53RAB9A | |
| SCHEMBL7145674 | 0.77 | PDE10A (0.50) | HPGDHSD17B10RAB9AMAPK1PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514989-B1 | Has a good affinity to the adenosine receptor and can therefore be used for the treatment or protection of diseases mediated by this receptor | HOFFMANN-LA ROCHE INC. | 2003-02-04 | — | — | US | disclosed |