Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.68 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.51 |
| ▸ | RELA | Q04206 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CLK1 | P49759 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16047420 | 0.88 | ALDH1A1 (0.64) | ALDH1A1KDM4EGFERL3MBTL1NPC1 | |
| SCHEMBL7076958 | 0.87 | ALDH1A1 (0.65) | ALDH1A1KDM4EGFERL3MBTL1NPC1 | |
| SCHEMBL25947756 | 0.81 | ALDH1A1 (1.00) | ALDH1A1KDM4EGFERL3MBTL1NPC1 | |
| SCHEMBL27581989 | 0.78 | KDM4E (0.64) | ALDH1A1KDM4EGFERL3MBTL1NPC1 | |
| SCHEMBL7076605 | 0.78 | ALDH1A1 (0.53) | ALDH1A1KDM4EGFERL3MBTL1NPC1 | |
| SCHEMBL14065435 | 0.77 | ALDH1A1 (0.78) | ALDH1A1KDM4EGFERL3MBTL1NPC1 | |
| SCHEMBL24373427 | 0.76 | KDM4E (0.57) | ALDH1A1KDM4EGFERL3MBTL1NPC1 | |
| SCHEMBL27581986 | 0.76 | KDM4E (0.61) | ALDH1A1KDM4EGFERL3MBTL1NPC1 | |
| SCHEMBL23151910 | 0.76 | GRM1 (0.42) | ALDH1A1KDM4EL3MBTL1RAB9AMAPT | |
| SCHEMBL473984 | 0.75 | ALDH1A1 (0.53) | ALDH1A1KDM4EL3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514991-B2 | Treating metabolic disorders mediated by insulin resistance or hyperglycemia; treating or inhibiting type 11 diabetes or urinary incontinence; increasing the lean meat to fat ratio in a mammal | WYETH | 2003-02-04 | — | — | US | disclosed |
| US-20020068751-A1 | Phenyl-oxo-tetrahydroquinolin-3-yl beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION | 2002-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020068751-A1 | Phenyl-oxo-tetrahydroquinolin-3-yl beta-3 adrenergic receptor agonists | ADRB1, ADRB3, ADRB2 | ALDH1A1 876/4885KDM4E 4227/4885GFER 2942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.