Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | POLQ | O75417 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.32 |
| ▸ | TYK2 | P29597 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6778823 | 0.63 | NPC1 (0.58) | NPC1POLBL3MBTL1ALDH1A1GAA | |
| SCHEMBL23846539 | 0.60 | NPC1 (0.55) | NPC1POLBL3MBTL1LMNAALDH1A1 | |
| SCHEMBL28871747 | 0.59 | PTGS2 (0.67) | NPC1L3MBTL1PTGS2LMNAALDH1A1 | |
| SCHEMBL31006494 | 0.59 | PTGS2 (0.67) | NPC1L3MBTL1PTGS2LMNAALDH1A1 | |
| SCHEMBL16363154 | 0.57 | S1PR1 (0.50) | ALDH1A1BRAFGPBAR1TYK2 | |
| SCHEMBL28871731 | 0.57 | ALDH1A1 (0.58) | NPC1L3MBTL1PTGS2ALDH1A1GAA | |
| SCHEMBL3833669 | 0.56 | NPC1 (0.58) | NPC1POLBALDH1A1TMPRSS4 | |
| SCHEMBL15236978 | 0.56 | POLB (0.65) | NPC1POLBLMNAALDH1A1 | |
| SCHEMBL9461862 | 0.56 | PTGS2 (0.67) | NPC1POLBPTGS2LMNAALDH1A1 | |
| SCHEMBL21261425 | 0.56 | ALDH1A1 (0.71) | NPC1POLBPTGS2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6521610-B2 | For controlling harmful insects, acarina and nematodes | HOECHST SCHERING AGREVO GMBH (DE) | 2003-02-18 | — | — | US | claimed |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | TIEBES JORG (DE) | 2002-01-31 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HAX1, HDHD5 | NPC1 3514/4885POLB 2336/4885L3MBTL1 1476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.