Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143055 | 0.87 | DRD4 (0.47) | MMP13CHRM1 | |
| SCHEMBL7146835 | 0.86 | SMN1; SMN2 (0.48) | MMP13KDM4EALDH1A1 | |
| SCHEMBL7147080 | 0.85 | EPHX2 (0.43) | CCR2EPHX2SCDMMP13 | |
| SCHEMBL7148150 | 0.85 | CHRM1 (0.46) | MMP13CHRM1ALDH1A1 | |
| SCHEMBL7146066 | 0.84 | MCHR1 (0.45) | KCNH2MMP13KDM4EALDH1A1 | |
| SCHEMBL7140914 | 0.84 | EPHX2 (0.42) | CCR2EPHX2SCDKCNH2MMP13 | |
| SCHEMBL7145387 | 0.84 | LMNA (0.45) | EPHX2MMP13CHRM1ALDH1A1 | |
| SCHEMBL7146510 | 0.84 | SENP5 (0.42) | MMP13CCR3ALDH1A1 | |
| SCHEMBL3479998 | 0.84 | KMT2A (0.50) | CCR2EPHX2SCDKCNH2ALDH1A1 | |
| SCHEMBL7146457 | 0.83 | CHRM1 (0.43) | MMP13CHRM1CCR3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1322642-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | Applied Research Systems ARS Holding N.V. (AN) | 2003-07-02 | — | — | EP | claimed |
| WO-2002026733-A2 | sHARMACEUTICALLY ACTIVE SULFONAMIDE DERIVATIVES BEARING BOTH LIPOPHILIC AND IONISABLE MOIETIES AS INHIBITORS OF PROTEIN JUNKINASES | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2002-04-04 | — | — | WO | claimed |