SCHEMBL714794

SCHEMBL714794

CCCc1ccc(-c2ccc(Br)c(F)c2)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RARB P10826 2/20 0.47
RARA P10276 1/20 0.47
RARG P13631 1/20 0.47
MCL1 Q07820 1/20 0.44
TAAR1 Q96RJ0 1/20 0.41
KIF11 P52732 2/20 0.41
NPC1 O15118 2/20 0.40
RAB9A P51151 2/20 0.40
TP53 P04637 1/20 0.40
PKM P14618 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 1/20 0.39
CTDSP1 Q9GZU7 1/20 0.39
MAOB P27338 1/20 0.39
ALOX5 P09917 1/20 0.38
MAPT P10636 1/20 0.38
GFER P55789 1/20 0.38
CA2 P00918 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8995495 0.90 RARB (0.55) RARBRARARARGNPC1RAB9A
SCHEMBL7788862 0.88 RARB (0.61) RARBRARARARGRAB9ATP53
SCHEMBL13564089 0.87 RARB (0.63) RARBRARARARGRAB9ATP53
SCHEMBL31371305 0.85 KIF11 (0.42) RARBRARARARGTAAR1KIF11
SCHEMBL8619701 0.85 CNR1 (0.44) NPC1RAB9ATP53PKMSMN1; SMN2
SCHEMBL222277 0.84 RARB (0.44) RARBRARARARGMCL1TAAR1
SCHEMBL16258014 0.83 CYP17A1 (0.53) RARBRARARARGMCL1TAAR1
SCHEMBL16258048 0.83 CYP17A1 (0.53) RARBRARARARGMCL1TAAR1
SCHEMBL9329120 0.81 CYP17A1 (0.51) RARBRARARARGMCL1TAAR1
SCHEMBL9512294 0.80 RARB (0.51) RARBRARARARGMCL1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120005633-A Liquid crystal compound and application thereof 石家庄诚志永华显示材料有限公司 2025-05-16 CN disclosed
CN-119307272-A Liquid crystal compound and application thereof 石家庄诚志永华显示材料有限公司 2025-01-14 CN disclosed
EP-2351727-B1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT AGC SEIMI CHEMICAL CO LTD (JP) 2014-07-23 EP disclosed
US-8283001-B2 Liquid crystal compound and process for production thereof, liquid crystal composition, and liquid crystal electrooptical element AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-10-09 US disclosed
US-8283001-B2 Liquid crystal compound and process for production thereof, liquid crystal composition, and liquid crystal electrooptical element AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-10-09 US disclosed
US-8273420-B2 Liquid crystal compound and process for production thereof, liquid crystal composition, and liquid crystal electrooptical element AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-09-25 US disclosed
US-8273420-B2 Liquid crystal compound and process for production thereof, liquid crystal composition, and liquid crystal electrooptical element AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-09-25 US disclosed
US-8273420-B2 Liquid crystal compound and process for production thereof, liquid crystal composition, and liquid crystal electrooptical element AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-09-25 US disclosed
US-20120105792-A1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-05-03 US disclosed
US-20120105792-A1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-05-03 US disclosed
US-20120050661-A1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-03-01 US disclosed
US-20120050661-A1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT AGC SEIMI CHEMICAL CO., LTD. (JP) 2012-03-01 US disclosed
EP-2351727-A1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT AGC Seimi Chemical Co., Ltd. (JP) 2011-08-03 EP disclosed
EP-2351727-A1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT AGC Seimi Chemical Co., Ltd. (JP) 2011-08-03 EP disclosed
EP-0535635-B1 Tolane derivative, liquid crystal composition containing the derivative, and liquid crystal display device using the composition SEIKO EPSON CORP (JP) 1996-08-21 EP disclosed
EP-0413785-B1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK PATENT GMBH (DE) 1995-12-20 EP disclosed
US-5437815-A Blending with ordinary liquid crystal compounds broadens practical temperature range of composition and produces an enlarged double refraction anisotropy SEIKO EPSON CORPORATION (JP) 1995-08-01 US disclosed
EP-0535635-A1 Tolane derivative, liquid crystal composition containing the derivative, and liquid crystal display device using the composition SEIKO EPSON CORPORATION (JP) 1993-04-07 EP disclosed
EP-0413785-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS. MERCK PATENT GMBH (DE) 1991-02-27 EP disclosed
WO-1990009420-A1 LIQUID CRYSTALLINE MEDIA CONTAINING FLUORINATED OLIGOPHENYLS MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1990-08-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120050661-A1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT CNOT9, AUP1, SFPQ RARB 3394/4885RARA 2781/4885RARG 2892/4885
US-20120105792-A1 LIQUID CRYSTAL COMPOUND AND PROCESS FOR PRODUCTION THEREOF, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL ELECTROOPTICAL ELEMENT HCN2, CPNE4, HCN1 RARB 2212/4885RARA 1917/4885RARG 3374/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.