SCHEMBL7148016

SCHEMBL7148016

Cc1ccc(-n2c3ccccc3c3cc(C=O)ccc32)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 5/20 0.52
KDM4E B2RXH2 5/20 0.49
ALDH1A1 P00352 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.44
ATM Q13315 1/20 0.44
CYP2A6 P11509 1/20 0.43
MAPT P10636 4/20 0.42
HTT P42858 4/20 0.42
LMNA P02545 1/20 0.42
AKR1C4 P17516 1/20 0.41
AKR1C3 P42330 1/20 0.41
AKR1C2 P52895 1/20 0.41
AKR1C1 Q04828 1/20 0.41
KIF11 P52732 1/20 0.40
POLB P06746 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 1/20 0.39
NPC1 O15118 1/20 0.39
HPGD P15428 1/20 0.39
RAB9A P51151 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8687231 0.92 CYP2A6 (0.50) PTGER4KDM4EALDH1A1CYP2A6MAPT
SCHEMBL18892915 0.91 KDM4E (0.49) PTGER4KDM4EALDH1A1L3MBTL1ATM
SCHEMBL17513001 0.91 KDM4E (0.54) PTGER4KDM4EALDH1A1L3MBTL1ATM
SCHEMBL3659204 0.88 PTGER4 (0.51) PTGER4KDM4EALDH1A1L3MBTL1ATM
SCHEMBL1199796 0.88 PTGER4 (0.51) PTGER4KDM4EALDH1A1L3MBTL1ATM
SCHEMBL7163446 0.88 KDM4E (0.60) PTGER4KDM4EALDH1A1L3MBTL1ATM
SCHEMBL28510264 0.85 PTGER4 (0.49) PTGER4KDM4EALDH1A1L3MBTL1ATM
SCHEMBL19718617 0.85 KDM4E (0.44) PTGER4KDM4EALDH1A1L3MBTL1ATM
SCHEMBL13040780 0.85 PTGER4 (0.49) PTGER4KDM4EALDH1A1L3MBTL1ATM
SCHEMBL22166478 0.85 PTGER4 (0.52) PTGER4KDM4EALDH1A1L3MBTL1ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107406383-B Compound for lithography, resin, and underlayer film forming material 三菱瓦斯化学株式会社 2021-01-26 CN disclosed
US-10696898-B2 Reverse photochromic compound FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2020-06-30 US disclosed
CN-101386602-B S-triazine derivates with white light and preparation method and application thereof UNIV SOUTH CHINA TECH 2011-05-18 CN disclosed
CN-101386602-A S-triazine derivates with white light and preparation method and application thereof UNIV SOUTH CHINA TECH (CN) 2009-03-18 CN disclosed
US-6528657-B2 For use in electroluminescence light emission element and can emit lights of various colors when an energy such as electric energy or electromagnetic energy is applied thereto TAIHO INDUSTRIES CO., LTD. (JP) 2003-03-04 US disclosed
US-20030023099-A1 Novel fluorescent carbazole derivative HIROSE ENGINEERING CO., LTD. (JP) 2003-01-30 US disclosed
US-5736284-A HIGH SOLUBILITY IN POLYMER BINDER TAKASAGO INTERNATIONAL CORPORATION (JP) 1998-04-07 US disclosed
US-4451548-A CARBAZOLE PHOTOCONDUCTOR KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1984-05-29 US disclosed
US-4415641-A AN N-ARYL, 3-/ARYL- OR HETEROCYCL VINYL-/CARBAZOLE; DURABILITY KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) 1983-11-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10696898-B2 Reverse photochromic compound CRY1, CRY2, C3AR1 PTGER4 24/4885KDM4E 2882/4885ALDH1A1 840/4885
US-20030023099-A1 Novel fluorescent carbazole derivative CBR3, AANAT, SIRT3 PTGER4 3447/4885KDM4E 3224/4885ALDH1A1 1143/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.