SCHEMBL714816

SCHEMBL714816

CC1[C]C2=CC=CCC(c3ccccc3)C2C1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.34
MAOA P21397 7/20 0.34
KDM1A O60341 5/20 0.34
CYP2C19 P33261 4/20 0.34
CYP2B6 P20813 3/20 0.34
HTR2C P28335 3/20 0.34
SLC6A2 P23975 3/20 0.34
SLC6A3 Q01959 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34
LMNA P02545 2/20 0.34
TAAR1 Q96RJ0 2/20 0.34
CYP3A4 P08684 1/20 0.34
HTR1A P08908 1/20 0.34
ADRA2A P08913 1/20 0.34
CYP2A6 P11509 1/20 0.34
ADRA1A P35348 1/20 0.34
DRD3 P35462 1/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6277769 0.77
Hydrochloric Acid SCHEMBL8736914 0.71 MAOB (0.34) MAOBMAOAKDM1ACYP2C19CYP2B6
Hydrochloric Acid SCHEMBL6683098 0.68 MAOB (0.35) MAOBMAOAKDM1ACYP2C19CYP2B6
SCHEMBL28230795 0.68 MAOB (0.52) MAOBMAOAKDM1ACYP2C19CYP2B6
Hydrochloric Acid SCHEMBL714598 0.66 MAOB (0.33) MAOBMAOAKDM1ACYP2C19CYP2B6
Hydrochloric Acid SCHEMBL8166710 0.65 MAOA (0.32) MAOBMAOAKDM1ACYP2C19CYP2B6
Hydrochloric Acid SCHEMBL8160548 0.64 MAOB (0.32) MAOBMAOAKDM1ALMNATAAR1
Hydrochloric Acid SCHEMBL8160547 0.64 NISCH (0.31) MAOBMAOA
Hydrochloric Acid SCHEMBL714104 0.64 NISCH (0.31) MAOBMAOA
Hydrochloric Acid SCHEMBL714105 0.64 MAOB (0.32) MAOBMAOAKDM1ALMNATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357765-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-22 US disclosed
US-8288490-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
US-20120053311-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
US-6943227-B2 Catalyst for olefin polymerization and method of polymerization of olefin JAPAN POLYPROPYLENE CORPORATION (JP) 2005-09-13 US disclosed
US-20040176242-A1 Catalyst for olefin polymerization and method of polymerization of olefin JAPAN POLYPROPYLENE CORPORATION (JP) 2004-09-09 US disclosed
EP-1416001-A1 CATALYST FOR OLEFIN POLYMERIZATION AND METHOD FOR POLYMERIZATION OF OLEFIN Japan Polychem Corporation (JP) 2004-05-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION PPOX, SOD1, AP1M1 MAOB 397/4885MAOA 102/4885KDM1A 3369/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.