Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 11/20 | 0.33 |
| ▸ | MAOA | P21397 | 10/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 5/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 5/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.31 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8736914 | 0.81 | MAOB (0.34) | MAOBMAOANISCHKDM1ACYP2C19 | |
| Hydrochloric Acid SCHEMBL6683098 | 0.78 | MAOB (0.35) | MAOBMAOANISCHKDM1ACYP2C19 | |
| Hydrochloric Acid SCHEMBL8166710 | 0.77 | MAOA (0.32) | MAOBMAOANISCHKDM1ACYP2C19 | |
| Hydrochloric Acid SCHEMBL714104 | 0.76 | NISCH (0.31) | MAOBMAOANISCH | |
| Hydrochloric Acid SCHEMBL8160547 | 0.76 | NISCH (0.31) | MAOBMAOANISCH | |
| Hydrochloric Acid SCHEMBL8160548 | 0.74 | MAOB (0.32) | MAOBMAOAKDM1ALMNATAAR1 | |
| Hydrochloric Acid SCHEMBL714105 | 0.74 | MAOB (0.32) | MAOBMAOAKDM1ALMNATAAR1 | |
| Hydrochloric Acid SCHEMBL8039642 | 0.73 | HDAC4 (0.32) | MAOBMAOAHDAC4KDM1ALMNA | |
| SCHEMBL714816 | 0.66 | MAOB (0.34) | MAOBMAOAHDAC4KDM1ACYP2C19 | |
| SCHEMBL28230795 | 0.64 | MAOB (0.52) | MAOBMAOAHDAC4KDM1ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357765-B2 | Process for producing catalyst component for addition polymerization | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-22 | — | — | US | disclosed |
| US-8288490-B2 | Process for producing catalyst component for addition polymerization | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20120053306-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120053311-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053306-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | PPOX, SOD1, AP1M1 | SLC6A2 4737/4885SLC6A3 4539/4885MAOB 397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.