Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30076618 | 0.81 | POLB (0.49) | POLBTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL4980531 | 0.80 | POLB (0.61) | POLBTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL9683795 | 0.78 | TDP1 (0.50) | POLBTDP1MEN1KMT2AKDM4E | |
| SCHEMBL17769822 | 0.77 | ALDH1A1 (0.55) | POLBTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL3161586 | 0.76 | GPR35 (0.51) | POLBTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL7080073 | 0.76 | PTPRC (0.41) | POLBTDP1MEN1KMT2AKDM4E | |
| SCHEMBL2552755 | 0.76 | ALDH1A1 (0.55) | POLBTDP1KMT2AALDH1A1LMNA | |
| SCHEMBL27401907 | 0.76 | HSD17B10 (0.55) | TDP1MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL4301056 | 0.75 | MEN1 (0.45) | POLBTDP1MEN1KMT2AALDH1A1 | |
| SCHEMBL11097917 | 0.75 | TSHR (0.44) | POLBTDP1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030219467-A1 | Method for the inhibition of methanogensis | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA | 2003-11-27 | — | — | US | disclosed |
| WO-2003038109-A2 | METHOD FOR THE INHIBITION OF METHANOGENESIS | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2003-05-08 | — | — | WO | disclosed |