Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | HPGDS | O60760 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | GALR2 | O43603 | 1/20 | 0.34 |
| ▸ | GALR1 | P47211 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142590 | 0.93 | HTR6 (0.37) | MAPTSMN1; SMN2POLBHPGDSALDH1A1 | |
| SCHEMBL7141760 | 0.91 | ROCK2 (0.33) | MAPTSMN1; SMN2GAALMNAHTT | |
| SCHEMBL7139375 | 0.91 | ENPP3 (0.37) | GPR17HTR6ENPP3ENPP1ENPP2 | |
| SCHEMBL7147110 | 0.87 | MEN1 (0.36) | MAPTHTTMEN1KMT2AHTR6 | |
| SCHEMBL7163606 | 0.84 | ENPP3 (0.35) | MAPTHTTMEN1KMT2AENPP3 | |
| SCHEMBL7141882 | 0.83 | ENPP3 (0.36) | MAPTHTTENPP3ENPP1ENPP2 | |
| SCHEMBL5037793 | 0.82 | ENPP3 (0.39) | MAPTHTTENPP3ENPP1ENPP2 | |
| SCHEMBL5040705 | 0.80 | ENPP3 (0.36) | MAPTSMN1; SMN2LMNAHTTMEN1 | |
| SCHEMBL7145205 | 0.79 | ENPP3 (0.36) | MAPTHTTENPP3ENPP1ENPP2 | |
| SCHEMBL5035960 | 0.79 | ENPP3 (0.39) | MAPTHTTENPP3ENPP1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1298125-A1 | Substituted benzimidazole compounds and their use for the treatment of cancer | Aventis Pharma S.A. (FR) | 2003-04-02 | — | — | EP | disclosed |