Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.42 |
| ▸ | SGMS1 | Q86VZ5 | 1/20 | 0.42 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL214099 | 0.85 | PTGS2 (0.54) | AKR1C3ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL6093446 | 0.85 | PTGS2 (0.54) | AKR1C3ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL29528338 | 0.85 | PTGS2 (0.54) | AKR1C3ALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL7142073 | 0.83 | PTGS2 (0.41) | LMNA | |
| SCHEMBL7148454 | 0.83 | PDK1 (0.45) | ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL7144308 | 0.82 | PTGS2 (0.43) | — | |
| SCHEMBL7140451 | 0.81 | MEN1 (0.46) | ALDH1A1MEN1KMT2ANPSR1MAPT | |
| SCHEMBL7145053 | 0.80 | PTGS2 (0.42) | ALDH1A1LMNA | |
| SCHEMBL7140517 | 0.78 | PTGS2 (0.46) | — | |
| SCHEMBL7143166 | 0.78 | PTGS2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |