Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 12/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144308 | 0.89 | PTGS2 (0.43) | PTGS2PTGS1P2RY6ADRA2ADRD5 | |
| SCHEMBL7140517 | 0.85 | PTGS2 (0.46) | PTGS2PTGS1P2RY6ADRA2ADRD5 | |
| SCHEMBL7146763 | 0.84 | HPGD (0.46) | PTGS2PTGS1ALDH1A1LMNA | |
| SCHEMBL7148454 | 0.84 | PDK1 (0.45) | PTGS2PTGS1P2RY6ALDH1A1LMNA | |
| SCHEMBL6093110 | 0.84 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL214422 | 0.84 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL29527245 | 0.84 | PTGS2 (0.61) | PTGS2PTGS1 | |
| SCHEMBL7143166 | 0.83 | PTGS2 (0.43) | PTGS2PTGS1P2RY6ADRA2ADRD5 | |
| SCHEMBL7145220 | 0.83 | PTGS2 (0.43) | PTGS2PTGS1P2RY6ADRA2ADRD5 | |
| SCHEMBL7140451 | 0.81 | MEN1 (0.46) | ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |