Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7146763 | 0.87 | HPGD (0.46) | MEN1KMT2APOLBMAPTALDH1A1 | |
| SCHEMBL214585 | 0.86 | PTGS2 (0.50) | MEN1KMT2APOLBMAPTUSP2 | |
| SCHEMBL6093632 | 0.86 | PTGS2 (0.50) | MEN1KMT2APOLBMAPTUSP2 | |
| SCHEMBL29527861 | 0.86 | PTGS2 (0.50) | MEN1KMT2APOLBMAPTUSP2 | |
| SCHEMBL7148773 | 0.81 | AKR1C3 (0.44) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL7148454 | 0.81 | PDK1 (0.45) | MEN1KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL7145053 | 0.81 | PTGS2 (0.42) | ALDH1A1LMNA | |
| SCHEMBL7144308 | 0.80 | PTGS2 (0.43) | — | |
| SCHEMBL7140517 | 0.77 | PTGS2 (0.46) | — | |
| SCHEMBL7143166 | 0.77 | PTGS2 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |