Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMBR | P28336 | 14/20 | 0.57 |
| ▸ | GRPR | P30550 | 7/20 | 0.57 |
| ▸ | FPR2 | P25090 | 5/20 | 0.52 |
| ▸ | FPR1 | P21462 | 3/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.44 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6255988 | 0.74 | FPR2 (0.44) | NMBRGRPRFPR2FPR1 | |
| SCHEMBL6251051 | 0.73 | NMBR (1.00) | NMBRGRPRFPR1AGTR1GPR65 | |
| SCHEMBL7149063 | 0.73 | TRPV1 (0.46) | FPR2 | |
| SCHEMBL1492709 | 0.70 | WNT3A (0.50) | NMBRGRPRFPR2FPR1 | |
| SCHEMBL13328404 | 0.70 | NMBR (0.64) | NMBR | |
| SCHEMBL6180757 | 0.69 | SLC6A9 (0.49) | NMBRGRPR | |
| SCHEMBL2731250 | 0.68 | TRPV1 (0.61) | — | |
| SCHEMBL6253853 | 0.68 | FPR2 (0.48) | NMBRGRPRFPR2FPR1 | |
| SCHEMBL7204980 | 0.67 | FPR2 (0.66) | NMBRGRPRFPR2FPR1AGTR1 | |
| SCHEMBL20379672 | 0.67 | NPC1 (0.72) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343498-A1 | NOVEL USES OF NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS FOR TREATING ANXIETY AND PANIC DISORDERS | Warner-Lambert Company LLC (US) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002049644-A1 | NOVEL USES OF NON-PEPTIDE BOMBESIN RECEPTOR ANTAGONISTS FOR TREATING ANXIETY AND PANIC DISORDERS | WARNER-LAMBERT COMPANY LLC (US) | 2002-06-27 | — | — | WO | disclosed |