Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.41 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 2/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.40 |
| ▸ | TYK2 | P29597 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6284630 | 0.99 | GAA (0.49) | GAAADRB3ATMHTTSMN1; SMN2 | |
| SCHEMBL7147778 | 0.83 | TYK2 (0.50) | SMN1; SMN2ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL7143404 | 0.82 | CYP11B2 (0.50) | HTTSMN1; SMN2ALDH1A1LMNACFTR | |
| Hydrochloric Acid SCHEMBL11490594 | 0.82 | GAA (0.54) | GAAADRB3ATMHTTSMN1; SMN2 | |
| Bromide SCHEMBL6280875 | 0.82 | TYK2 (0.49) | SMN1; SMN2ALDH1A1SLC6A2SLC6A4SLC6A3 | |
| Bromide SCHEMBL6283092 | 0.81 | CYP11B2 (0.49) | HTTSMN1; SMN2ALDH1A1LMNACFTR | |
| SCHEMBL7140967 | 0.78 | SMN1; SMN2 (0.51) | GAAHTTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL7142799 | 0.78 | NAMPT (0.49) | GAASMN1; SMN2ALDH1A1LMNAKCNA5 | |
| Bromide SCHEMBL6282444 | 0.77 | SMN1; SMN2 (0.50) | GAAHTTSMN1; SMN2ALDH1A1LMNA | |
| Bromide SCHEMBL6276160 | 0.77 | NAMPT (0.48) | GAASMN1; SMN2ALDH1A1LMNAKCNA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |