SCHEMBL7149223

SCHEMBL7149223

CC(C)C[Al](Oc1ccc(C(C)(C)C)cc1C(C)(C)C)c1c(F)c(F)c(F)c(F)c1F

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.33
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7151819 0.80 RXRA (0.31)
SCHEMBL3326157 0.79 ATM (0.40) ATML3MBTL1KDM4E
SCHEMBL7151824 0.78 ATM (0.37) ATML3MBTL1
SCHEMBL7153443 0.75 ALDH1A1 (0.32)
SCHEMBL4860344 0.67 RXRA (0.41) ATMKDM4E
SCHEMBL7633522 0.67 ATM (0.38) ATML3MBTL1
SCHEMBL13019327 0.66 CA1 (0.40) ATML3MBTL1KDM4E
SCHEMBL9350606 0.65 ATM (0.40) ATML3MBTL1KDM4E
SCHEMBL28425202 0.65 CA1 (0.44) ATML3MBTL1KDM4E
SCHEMBL27170735 0.64 KDM4E (0.45) ATMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1105397-B1 THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION DOW GLOBAL TECHNOLOGIES INC (US) 2003-03-05 EP disclosed
US-6528449-B1 Polymerization catalysts such as /tertbutylamido/tetramethyl-cyclopentadienyl/ dimethylsilanetitanium 1,3-pentadiene and isobutyl(perfluorophenyl)-4,6-di-(t-butyl) phenoxyaluminum THE DOW CHEMICAL COMAPNY 2003-03-04 US disclosed
EP-1105398-B1 ACTIVATOR COMPOSITION COMPRISING ALUMINUM COMPOUND MIXTURE DOW CHEMICAL CO (US) 2002-07-17 EP disclosed
US-6387838-B2 ALUMINUM COMPOUND WITH AT LEAST ONE FLUORINATED AROMATIC HYDROCARBYL MOIETY AND A METAL COMPLEX IN GIVEN MOLAR RATIO; ADDITION POLYMERIZATION OF OLEFINS, DIOLEFINS, AND CYCLIC OLEFINS THE DOW CHEMICAL COMPANY 2002-05-14 US disclosed
US-20010018396-A1 Activator composition comprising aluminum compound mixture CHEN EUGENE Y (US) 2001-08-30 US disclosed
EP-1105397-A1 THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION THE DOW CHEMICAL COMPANY (US) 2001-06-13 EP disclosed
EP-1105398-A1 ACTIVATOR COMPOSITION COMPRISING ALUMINUM COMPOUND MIXTURE THE DOW CHEMICAL COMPANY (US) 2001-06-13 EP disclosed
US-6211111-B1 Activator composition comprising aluminum compound mixture THE DOW CHEMICAL COMPANY 2001-04-03 US disclosed
US-6187940-B1 A FLUORINATED AROMATIC HYDROCARBYL ALUMINUM COMPOUND USE AS ACTIVATORS FOR ACTIVATION OF METAL COMPLEXES IN OLEFIN POLYMERIZATIONS; IMPROVED EFFICIENCY AND OPERABILITY THE DOW CHEMICAL COMPANY 2001-02-13 US disclosed
WO-2000009514-A1 ACTIVATOR COMPOSITION COMPRISING ALUMINUM COMPOUND MIXTURE THE DOW CHEMICAL COMPANY (US) 2000-02-24 WO disclosed
WO-2000009513-A1 THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION THE DOW CHEMICAL COMPANY (US) 2000-02-24 WO disclosed