SCHEMBL7633522

SCHEMBL7633522

CC(C)Cc1c(F)c(F)c(F)c(F)c1[Al]Oc1ccc(C(C)(C)C)cc1C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7151824 0.75 ATM (0.37) ATML3MBTL1
SCHEMBL7149223 0.67 ATM (0.34) ATML3MBTL1
SCHEMBL18948601 0.64 L3MBTL1 (0.38) ATML3MBTL1
SCHEMBL13019327 0.64 CA1 (0.40) ATML3MBTL1
SCHEMBL15191818 0.63 CA1 (0.42) ATML3MBTL1
SCHEMBL15191820 0.63 CA1 (0.42) ATML3MBTL1
SCHEMBL25020562 0.63 TP53 (0.41) ATM
SCHEMBL3326157 0.63 ATM (0.40) ATML3MBTL1
SCHEMBL9350606 0.63 ATM (0.40) ATML3MBTL1
SCHEMBL28425202 0.62 CA1 (0.44) ATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1105398-B1 ACTIVATOR COMPOSITION COMPRISING ALUMINUM COMPOUND MIXTURE DOW CHEMICAL CO (US) 2002-07-17 EP disclosed
US-6387838-B2 ALUMINUM COMPOUND WITH AT LEAST ONE FLUORINATED AROMATIC HYDROCARBYL MOIETY AND A METAL COMPLEX IN GIVEN MOLAR RATIO; ADDITION POLYMERIZATION OF OLEFINS, DIOLEFINS, AND CYCLIC OLEFINS THE DOW CHEMICAL COMPANY 2002-05-14 US disclosed
US-20010018396-A1 Activator composition comprising aluminum compound mixture CHEN EUGENE Y (US) 2001-08-30 US disclosed
EP-1105398-A1 ACTIVATOR COMPOSITION COMPRISING ALUMINUM COMPOUND MIXTURE THE DOW CHEMICAL COMPANY (US) 2001-06-13 EP disclosed
US-6211111-B1 Activator composition comprising aluminum compound mixture THE DOW CHEMICAL COMPANY 2001-04-03 US disclosed
WO-2000009514-A1 ACTIVATOR COMPOSITION COMPRISING ALUMINUM COMPOUND MIXTURE THE DOW CHEMICAL COMPANY (US) 2000-02-24 WO disclosed