Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.59 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.56 |
| ▸ | IKBKB | O14920 | 1/20 | 0.55 |
| ▸ | CHUK | O15111 | 1/20 | 0.55 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.49 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7415408 | 0.92 | NFE2L2 (0.55) | NFE2L2TRPM8IKBKBCHUKIKBKG | |
| SCHEMBL20970610 | 0.85 | NFE2L2 (0.58) | NFE2L2TRPM8IKBKBCHUKIKBKG | |
| SCHEMBL14462725 | 0.85 | NFE2L2 (0.59) | NFE2L2TRPM8IKBKBCHUKIKBKG | |
| SCHEMBL998236 | 0.84 | LMNA (0.64) | NFE2L2LMNAKDM4EKMT2APKM | |
| SCHEMBL28955118 | 0.81 | NFE2L2 (0.54) | NFE2L2TRPM8IKBKBCHUKIKBKG | |
| SCHEMBL7311454 | 0.81 | KMT2A (0.54) | NFE2L2TRPM8LMNAKDM4EHPGD | |
| SCHEMBL10666690 | 0.81 | NFE2L2 (0.55) | NFE2L2TRPM8IKBKBCHUKIKBKG | |
| SCHEMBL7814194 | 0.80 | KDM4E (0.76) | NFE2L2TRPM8LMNAKDM4EHPGD | |
| SCHEMBL7814195 | 0.80 | KDM4E (0.76) | NFE2L2TRPM8LMNAKDM4EHPGD | |
| SCHEMBL9493170 | 0.79 | CA12 (0.52) | NFE2L2LMNAKDM4EHPGDCYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | MERCK PATENT GMBH (DE) | 2018-07-26 | — | — | US | disclosed |
| US-20120052028-A1 | CINNAMIC ACID ASCORBATES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180207080-A1 | COMPOSITIONS OF FLUORINATED SURFACTANTS AND ANTIOXIDANTS | LPO, CAT, GPX4 | NFE2L2 114/4885TRPM8 3441/4885IKBKB 3000/4885 |
| US-20120052028-A1 | CINNAMIC ACID ASCORBATES | PROC, C1S, NISCH | NFE2L2 70/4885TRPM8 1681/4885IKBKB 1274/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.