Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10945950 | 0.80 | SMPD1 (0.48) | SMPD1OPRM1SPHK1LMNADNM1 | |
| Hydrochloric Acid SCHEMBL10778343 | 0.78 | SMPD1 (0.47) | SMPD1OPRM1SPHK1LMNADNM1 | |
| SCHEMBL15377303 | 0.77 | OPRM1 (0.48) | SMPD1OPRM1SPHK1LMNADNM1 | |
| SCHEMBL11493629 | 0.76 | SMPD1 (0.50) | SMPD1SPHK1LMNADNM1TSHR | |
| SCHEMBL11490676 | 0.76 | SMPD1 (0.50) | SMPD1SPHK1LMNADNM1TSHR | |
| SCHEMBL1400448 | 0.76 | OPRM1 (0.48) | OPRM1SPHK1LMNACYP2D6PLA2G1B | |
| SCHEMBL9751259 | 0.74 | SMPD1 (0.44) | SMPD1OPRM1LMNADNM1TSHR | |
| SCHEMBL77792 | 0.73 | SMPD1 (0.47) | SMPD1OPRM1SPHK1LMNADNM1 | |
| SCHEMBL31379942 | 0.73 | SMPD1 (0.47) | SMPD1OPRM1SPHK1LMNADNM1 | |
| SCHEMBL873446 | 0.72 | SMPD1 (0.50) | SMPD1OPRM1SPHK1LMNADNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6448394-B1 | FORMATION OF BLOCKED ISOCYANTES WITHOUT FREE ISOCYANATE PRESENT BY REACTING AMINE WITH CARBONIC ACID DERIVATIVE | DSM N.V. (NL) | 2002-09-10 | — | — | US | claimed |
| US-20030088020-A1 | Powder paint binder composition | DSM N.V. (NL) | 2003-05-08 | — | — | US | disclosed |
| EP-1263829-A1 | POWDER PAINT BINDER COMPOSITION | DSM N.V. (NL) | 2002-12-11 | — | — | EP | disclosed |
| US-6448394-B1 | FORMATION OF BLOCKED ISOCYANTES WITHOUT FREE ISOCYANATE PRESENT BY REACTING AMINE WITH CARBONIC ACID DERIVATIVE | DSM N.V. (NL) | 2002-09-10 | — | — | US | disclosed |
| US-20020028932-A1 | Process for the preparation of an N-alkyl or N-aryl carbamoyl derivative | DSM IP ASSETS B.V. (NL) | 2002-03-07 | — | — | US | disclosed |
| WO-2001064769-A1 | POWDER PAINT BINDER COMPOSITION | DSM N.V. (NL) | 2001-09-07 | — | — | WO | disclosed |
| EP-1130039-A1 | Powder paint binder composition | DSM N.V. (NL) | 2001-09-05 | — | — | EP | disclosed |
| EP-1115709-A1 | PROCESS FOR THE PREPARATION OF AN N-ALKYL OR N-ARYL CARBAMOYL DERIVATIVE | DSM N.V. (NL) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000017169-A1 | PROCESS FOR THE PREPARATION OF AN N-ALKYL OR N-ARYL CARBAMOYL DERIVATIVE | DSM N.V. (NL) | 2000-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020028932-A1 | Process for the preparation of an N-alkyl or N-aryl carbamoyl derivative | OGDH, DOHH, CFH | SMPD1 1802/4885OPRM1 3009/4885SPHK1 4588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.