SCHEMBL715045

SCHEMBL715045

[c]1ccccc1-c1cccc(-c2ccccc2)n1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.61
KMT2A Q03164 4/20 0.61
RAB9A P51151 3/20 0.61
ASIC3 Q9UHC3 1/20 0.47
ALDH1A1 P00352 5/20 0.41
HPGD P15428 3/20 0.41
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
HSD17B10 Q99714 1/20 0.41
ADORA2A P29274 2/20 0.36
HSP90AA1 P07900 2/20 0.36
AURKA O14965 1/20 0.36
PRKACA P17612 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
ADORA1 P30542 1/20 0.35
HTR1A P08908 1/20 0.35
DRD2 P14416 1/20 0.35
HTR2A P28223 1/20 0.35
HTR7 P34969 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4406097 0.81 MEN1 (0.94) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL715745 0.78 RAB9A (0.44) MEN1KMT2ARAB9AHPGDMAPT
SCHEMBL58442 0.78 MEN1 (1.00) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL714994 0.77 CCR1 (0.56) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL9958776 0.77 MEN1 (0.48) MEN1KMT2ARAB9AALDH1A1HPGD
SCHEMBL4717451 0.77 TGFBR1 (0.33) MEN1KMT2ARAB9AHSD17B10
SCHEMBL16077969 0.76 MEN1 (0.94) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL5945940 0.76 MEN1 (0.94) MEN1KMT2ARAB9AASIC3ALDH1A1
Bromide SCHEMBL10753629 0.76 MEN1 (0.94) MEN1KMT2ARAB9AASIC3ALDH1A1
SCHEMBL715046 0.75 MEN1 (0.73) MEN1KMT2ARAB9AASIC3ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109311844-B Triazine compound, method for producing same, and organic electroluminescent element containing same as constituent component 东曹株式会社 2021-07-20 CN disclosed
US-8771843-B2 Fluorene derivative, organic compound, and light-emitting element, light-emitting device, and electronic device using the compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-07-08 US disclosed
US-20120049768-A1 Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120049768-A1 Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound AFF2, MAPRE2, AFF4 MEN1 1673/4885KMT2A 2499/4885RAB9A 440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.