Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.43 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 7/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | DRD4 | P21917 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27590549 | 0.86 | HRH3 (0.40) | CYP2D6CYP2C19HRH3GNAO1HRH1 | |
| SCHEMBL27357785 | 0.86 | HRH3 (0.55) | CYP2D6CYP2C19HRH3GNAO1HRH1 | |
| SCHEMBL4378930 | 0.82 | HSD11B1 (0.39) | HRH3GNAO1DRD2DRD3 | |
| SCHEMBL19446344 | 0.82 | CYP2D6 (0.44) | CYP2D6CYP2C19HRH3GNAO1HRH1 | |
| SCHEMBL3948738 | 0.80 | GNAO1 (0.45) | HRH3GNAO1HRH1CHRM1CHRM2 | |
| SCHEMBL22924119 | 0.76 | CYP2D6 (0.45) | CYP2D6CYP2C19HRH3GNAO1HRH1 | |
| SCHEMBL830929 | 0.76 | CYP2D6 (0.49) | CYP2D6CYP2C19HRH3KDM4EHSD17B10 | |
| SCHEMBL25907681 | 0.76 | CYP2D6 (0.38) | CYP2D6CYP2C19HRH3GNAO1HRH1 | |
| SCHEMBL3955899 | 0.75 | SMN1; SMN2 (0.45) | HRH3GNAO1 | |
| SCHEMBL13602614 | 0.75 | CYP2D6 (0.42) | CYP2D6CYP2C19HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030207878-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2003-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207878-A1 | Chemical compounds | CYP3A7, HTR3C, CNR1 | CYP2D6 301/4885CYP2C19 179/4885HRH3 44/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.