Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153206 | 0.99 | RAB9A (0.53) | RAB9ANPC1ALDH1A1POLBKMT2A | |
| SCHEMBL7157515 | 0.87 | NPC1 (0.54) | RAB9ANPC1ALDH1A1POLBKMT2A | |
| SCHEMBL7157379 | 0.87 | NPY2R (0.60) | RAB9ANPC1ALDH1A1POLBKMT2A | |
| SCHEMBL7152061 | 0.86 | NPC1 (0.53) | RAB9ANPC1ALDH1A1POLBKMT2A | |
| SCHEMBL7150740 | 0.85 | NPC1 (0.57) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL1377368 | 0.85 | ALDH1A1 (0.49) | RAB9AALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL6140496 | 0.85 | RAB9A (0.51) | RAB9ANPC1ALDH1A1POLBKMT2A | |
| SCHEMBL7150794 | 0.85 | NPC1 (0.56) | RAB9ANPC1ALDH1A1KMT2AMEN1 | |
| SCHEMBL6140081 | 0.84 | LMNA (0.47) | RAB9ANPC1ALDH1A1POLBKMT2A | |
| SCHEMBL7185405 | 0.83 | RAB9A (0.51) | RAB9ANPC1ALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | claimed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | claimed |
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | disclosed |