Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 6/20 | 0.46 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150787 | 0.83 | RAB9A (0.54) | RAB9ASMN1; SMN2POLBCYP3A4CYP2C19 | |
| SCHEMBL6140496 | 0.83 | RAB9A (0.51) | RAB9ASMN1; SMN2POLBCYP3A4CYP2C19 | |
| SCHEMBL7153206 | 0.82 | RAB9A (0.53) | RAB9ASMN1; SMN2POLBCYP3A4CYP2C19 | |
| SCHEMBL7147258 | 0.80 | NPC1 (0.49) | RAB9ASMN1; SMN2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL5165701 | 0.77 | F10 (0.44) | — | |
| SCHEMBL8270932 | 0.77 | HTR1A (0.34) | RAB9AALDH1A1KMT2AMEN1MAPT | |
| SCHEMBL6140081 | 0.76 | LMNA (0.47) | RAB9ASMN1; SMN2POLBCYP3A4CYP2C19 | |
| SCHEMBL6918329 | 0.73 | POLB (0.67) | RAB9ASMN1; SMN2POLBCYP3A4CYP2C19 | |
| SCHEMBL11317939 | 0.72 | POLB (0.60) | RAB9ASMN1; SMN2POLBALDH1A1KDM4E | |
| SCHEMBL7154949 | 0.72 | POLB (0.50) | RAB9ASMN1; SMN2POLBCYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | claimed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | claimed |