Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | APP | P05067 | 4/20 | 0.53 |
| ▸ | TSPO | P30536 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2628204 | 1.00 | ALDH1A1 (0.58) | ALDH1A1POLBAPPTSPOKDM4E | |
| SCHEMBL7153441 | 0.87 | POLB (0.56) | ALDH1A1POLBKDM4ECYP1A2CYP2D6 | |
| SCHEMBL10897821 | 0.86 | POLB (0.54) | POLBKDM4ECYP1A2CYP2D6PDE4A | |
| SCHEMBL9826297 | 0.86 | POLB (0.54) | ALDH1A1POLBKDM4ECYP1A2CYP2D6 | |
| Ethylene SCHEMBL10898008 | 0.84 | POLB (0.53) | ALDH1A1POLBKDM4ECYP1A2CYP2D6 | |
| SCHEMBL9632476 | 0.84 | LMNA (0.60) | ALDH1A1POLBKDM4ECYP1A2CYP2D6 | |
| SCHEMBL2628195 | 0.84 | PLA2G4B (0.55) | ALDH1A1APPL3MBTL1LMNA | |
| SCHEMBL8347541 | 0.84 | KDM4E (0.68) | ALDH1A1POLBKDM4ECYP1A2CYP2D6 | |
| SCHEMBL2628191 | 0.84 | PLA2G4B (0.55) | ALDH1A1APPL3MBTL1LMNA | |
| SCHEMBL9826466 | 0.83 | GAA (0.54) | ALDH1A1POLBKDM4ECYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120100073-A1 | PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE | WASHINGTON UNIVERSITY (US) | 2012-04-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120100073-A1 | PET RADIOTRACERS FOR IMAGING FATTY ACID METABOLISM AND STORAGE | LIPC, PNLIP, FFAR1 | ALDH1A1 838/4885POLB 3372/4885APP 1821/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.