⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7153443 | 0.76 | ALDH1A1 (0.32) | — | |
| SCHEMBL7150668 | 0.73 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL7147141 | 0.72 | SMN1; SMN2 (0.37) | — | |
| SCHEMBL585549 | 0.68 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL78216 | 0.68 | SMN1; SMN2 (0.38) | — | |
| SCHEMBL7151824 | 0.68 | ATM (0.37) | — | |
| SCHEMBL7629704 | 0.66 | — | — | |
| SCHEMBL77412 | 0.64 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL7151819 | 0.63 | RXRA (0.31) | — | |
| SCHEMBL585928 | 0.63 | SMN1; SMN2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1105397-B1 | THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION | DOW GLOBAL TECHNOLOGIES INC (US) | 2003-03-05 | — | — | EP | disclosed |
| US-6528449-B1 | Polymerization catalysts such as /tertbutylamido/tetramethyl-cyclopentadienyl/ dimethylsilanetitanium 1,3-pentadiene and isobutyl(perfluorophenyl)-4,6-di-(t-butyl) phenoxyaluminum | THE DOW CHEMICAL COMAPNY | 2003-03-04 | — | — | US | disclosed |
| EP-1105397-A1 | THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 2001-06-13 | — | — | EP | disclosed |
| US-6187940-B1 | A FLUORINATED AROMATIC HYDROCARBYL ALUMINUM COMPOUND USE AS ACTIVATORS FOR ACTIVATION OF METAL COMPLEXES IN OLEFIN POLYMERIZATIONS; IMPROVED EFFICIENCY AND OPERABILITY | THE DOW CHEMICAL COMPANY | 2001-02-13 | — | — | US | disclosed |
| WO-2000009513-A1 | THREE COORDINATE ALUMINUM CATALYST ACTIVATOR COMPOSITION | THE DOW CHEMICAL COMPANY (US) | 2000-02-24 | — | — | WO | disclosed |