Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.62 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.59 |
| ▸ | CFTR | P13569 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.56 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.56 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7111034 | 0.91 | MEN1 (0.66) | ALOX5CFTRMEN1ALDH1A1KMT2A | |
| SCHEMBL7115739 | 0.87 | ALOX5 (0.81) | ALOX5NPY5RCFTRMEN1KMT2A | |
| SCHEMBL29654163 | 0.85 | CYP1B1 (0.69) | ALOX5NPY5RCFTRMEN1ALDH1A1 | |
| SCHEMBL28712018 | 0.85 | CYP1B1 (0.69) | ALOX5NPY5RCFTRMEN1ALDH1A1 | |
| SCHEMBL181004 | 0.84 | CYP1A1 (0.70) | ALOX5NPY5RCFTRMEN1ALDH1A1 | |
| SCHEMBL28701564 | 0.82 | CYP1B1 (0.77) | ALOX5NPY5RCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL12297865 | 0.81 | ALOX5 (0.74) | ALOX5NPY5RCFTRMEN1ALDH1A1 | |
| SCHEMBL12297203 | 0.80 | ALOX5 (0.72) | ALOX5NPY5RCFTRMEN1ALDH1A1 | |
| SCHEMBL7109635 | 0.79 | ALOX5 (0.74) | ALOX5NPY5RMEN1KMT2ACYP1A1 | |
| SCHEMBL1885179 | 0.79 | MEN1 (0.77) | ALOX5CFTRMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030220380-A1 | Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1 | 3-DIMENSIONAL PHARMACEUTICALS, INC. | 2003-11-27 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030220380-A1 | Substituted thiazoles and the use thereof as inhibitors of plasminogen activator inhibitor-1 | SERPINE1, SERPINC1, SERPINB1 | ALOX5 2040/4885NPY5R 936/4885CFTR 1647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.