Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ACP3 | P15309 | 1/20 | 0.50 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11991724 | 0.91 | KIF11 (0.48) | KIF11ALDH1A1TSHRACP3TRPV6 | |
| SCHEMBL6204533 | 0.91 | KIF11 (0.48) | KIF11ALDH1A1TSHRACP3TRPV6 | |
| SCHEMBL11991723 | 0.88 | KIF11 (0.43) | KIF11ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL15698268 | 0.87 | PTPN5 (0.47) | KIF11ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL11991747 | 0.86 | KIF11 (0.56) | KIF11PTPN5 | |
| SCHEMBL7616716 | 0.83 | P2RX1 (0.46) | KIF11ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL15700305 | 0.83 | PTPN5 (0.44) | KIF11ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL8164654 | 0.82 | PGK1 (0.51) | KIF11ALDH1A1TSHRRAB9AACP3 | |
| SCHEMBL11991725 | 0.81 | KIF11 (0.42) | KIF11ALDH1A1TSHRNPC1RAB9A | |
| SCHEMBL11991735 | 0.81 | KIF11 (0.42) | KIF11ALDH1A1TSHRNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117362339-A | Preparation and application of organic phosphine oxide compound | 浙江扬帆新材料股份有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-115055207-B | Method for preparing aryl phosphine by reducing aryl phosphine oxide | 清华大学 | 2023-07-21 | — | — | CN | disclosed |
| CN-115055207-A | Method for preparing aryl phosphine by reducing aryl phosphine oxide | 清华大学 | 2022-09-16 | — | — | CN | disclosed |
| US-6531633-B2 | Grignard reaction of bromobenzene substituted with fluoroalkyl group and diphenylphosphinic chloride in an organic solvent and magnesium, followed by nitration in sulfuric and nitric acids and hydrogenation in presence of palladium | KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-03-11 | — | — | US | disclosed |
| US-20020095057-A1 | Triarylphosphine oxide derivatives containing fluorine substituent and preparing method thereof | KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2002-07-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020095057-A1 | Triarylphosphine oxide derivatives containing fluorine substituent and preparing method thereof | PFAS, PTK2, PARP1 | KIF11 760/4885ALDH1A1 3785/4885TSHR 1457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.