SCHEMBL7154192

SCHEMBL7154192

CCCCOC(=O)N(OC)c1nnnc(N(OC)C(=O)OCCCC)c1N(OC)C(=O)OCCCC

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
RAB9A P51151 2/20 0.37
ATM Q13315 1/20 0.35
LMNA P02545 3/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
NPC1 O15118 1/20 0.35
TSHR P16473 5/20 0.34
L3MBTL1 Q9Y468 3/20 0.34
TDP1 Q9NUW8 1/20 0.34
HSD17B10 Q99714 3/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33
ESR1 P03372 3/20 0.33
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33
CYP2D6 P10635 1/20 0.33
MAPK1 P28482 1/20 0.33
NR1H2 P55055 1/20 0.33
RNASEL Q05823 1/20 0.33
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7154191 0.76 ALDH1A1 (0.42) ALDH1A1RAB9AATMLMNASMN1; SMN2
SCHEMBL4422288 0.71 LMNA (0.38) ALDH1A1ATMLMNASMN1; SMN2NPC1
SCHEMBL8773038 0.67 ALDH1A1 (0.50) ALDH1A1RAB9AATMLMNASMN1; SMN2
SCHEMBL8908162 0.64 CHRNB2 (0.58) ALDH1A1RAB9AATMLMNASMN1; SMN2
SCHEMBL7772397 0.62 ALDH1A1 (0.54) ALDH1A1RAB9AATMLMNASMN1; SMN2
SCHEMBL8909377 0.62 ALDH1A1 (0.54) ALDH1A1ATMLMNASMN1; SMN2TSHR
SCHEMBL996345 0.62 ALDH1A1 (0.54) ALDH1A1ATMLMNASMN1; SMN2TSHR
SCHEMBL27310028 0.62 ALDH1A1 (0.53) ALDH1A1ATMLMNASMN1; SMN2TSHR
SCHEMBL11747354 0.61 ALDH1A1 (0.58) ALDH1A1RAB9AATMLMNASMN1; SMN2
SCHEMBL15303488 0.61 ALDH1A1 (0.52) ALDH1A1ATMLMNASMN1; SMN2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0849283-B1 Non-aqueous polymer dispersion and curable composition KANSAI PAINT CO LTD (JP) 2003-06-18 EP disclosed
US-5929158-A FLUOROACRYLIC POLYMER WITH A DISPERSANT STABILIZER OF HYDROXY-CONTAINING RESINS AND CURING AGENT; PROTECTIVE COATINGS; WATER- AND WEATHERPROOFING; OIL REPELLANCY; ANTISOILANTS; AUTOMOBILE TOPCOATS KANSAI PAINT COMPANY, LIMITED (JP) 1999-07-27 US disclosed
EP-0849283-A2 Non-aqueous polymer dispersion and curable composition KANSAI PAINT CO., LTD. (JP) 1998-06-24 EP disclosed