Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
| ▸ | STAT3 | P40763 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15263575 | 0.88 | LMNA (0.38) | LMNAL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL15263572 | 0.83 | L3MBTL1 (0.43) | LMNAL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL7154191 | 0.83 | ALDH1A1 (0.42) | LMNAL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL16568444 | 0.73 | L3MBTL1 (0.39) | LMNAL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL7154192 | 0.71 | ALDH1A1 (0.37) | LMNAL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL5265758 | 0.70 | ALDH1A1 (0.42) | LMNAL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL11795523 | 0.70 | ALDH1A1 (0.40) | LMNAL3MBTL1TSHRALDH1A1CYP1A2 | |
| SCHEMBL7238236 | 0.69 | LMNA (0.51) | LMNAL3MBTL1TSHRTDP1ALDH1A1 | |
| SCHEMBL996720 | 0.68 | L3MBTL1 (0.55) | LMNAL3MBTL1TSHRALDH1A1CYP1A2 | |
| SCHEMBL5159308 | 0.67 | MLYCD (0.36) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090239435-A1 | PROTECTIVE SUIT AND METHODS OF MANUFACTURE THEREOF | GENERAL ELECTRIC COMPANY (US) | 2009-09-24 | — | — | US | disclosed |