Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL476985 | 0.97 | TSHR (0.47) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| Hydrochloric Acid SCHEMBL853896 | 0.93 | KDM4E (0.50) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| Iodide SCHEMBL2352341 | 0.93 | TSHR (0.44) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| Fluoride Ion SCHEMBL17870608 | 0.93 | TSHR (0.44) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| Water SCHEMBL319959 | 0.93 | TSHR (0.44) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| Bromide SCHEMBL8461151 | 0.93 | MEN1 (0.47) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| Hydrochloric Acid SCHEMBL2581079 | 0.93 | KDM4E (0.50) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| Water SCHEMBL27490218 | 0.93 | TSHR (0.44) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| SCHEMBL1686254 | 0.90 | TSHR (0.47) | KDM4EPMP22ATMCYP3A4SLC5A7 | |
| SCHEMBL1686196 | 0.90 | TSHR (0.47) | KDM4EPMP22ATMCYP3A4SLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118240288-B | Modified rubber powder and preparation method thereof, composition for non-cured waterproof coating, high-viscosity non-cured waterproof coating and preparation method thereof | 福建科顺新材料有限公司 | 2024-12-03 | — | — | CN | claimed |
| CN-118240288-A | Modified rubber powder and preparation method thereof, composition for non-cured waterproof coating, high-viscosity non-cured waterproof coating and preparation method thereof | 福建科顺新材料有限公司 | 2024-06-25 | — | — | CN | claimed |
| CN-113417029-B | Elastic sea island filament and production process thereof | 杭州惠丰化纤有限公司 | 2022-09-16 | — | — | CN | claimed |
| CN-121248944-A | Block copolymer well wall strengthening agent rich in positive charge anchor points, and preparation method and application thereof | 中石化石油工程技术服务股份有限公司 | 2026-01-02 | — | — | CN | disclosed |
| CN-118240288-B | Modified rubber powder and preparation method thereof, composition for non-cured waterproof coating, high-viscosity non-cured waterproof coating and preparation method thereof | 福建科顺新材料有限公司 | 2024-12-03 | — | — | CN | disclosed |
| CN-118240288-A | Modified rubber powder and preparation method thereof, composition for non-cured waterproof coating, high-viscosity non-cured waterproof coating and preparation method thereof | 福建科顺新材料有限公司 | 2024-06-25 | — | — | CN | disclosed |
| US-20240174862-A1 | EUTECTIC MIXTURE AND LIQUID COMPOSITION | DAICEL CORPORATION (JP) | 2024-05-30 | — | — | US | disclosed |
| EP-4317127-A1 | EUTECTIC MIXTURE AND LIQUID COMPOSITION | Daicel Corporation (JP) | 2024-02-07 | — | — | EP | disclosed |
| CN-113481624-B | Polyester yarn and production process thereof | 杭州惠丰化纤有限公司 | 2023-04-28 | — | — | CN | disclosed |
| WO-2022201519-A1 | EUTECTIC MIXTURE AND LIQUID COMPOSITION | 株式会社ダイセル | 2022-09-29 | — | — | WO | disclosed |
| CN-113417029-B | Elastic sea island filament and production process thereof | 杭州惠丰化纤有限公司 | 2022-09-16 | — | — | CN | disclosed |
| US-20140054200-A1 | ANALOGUE IONIC LIQUIDS FOR THE SEPARATION AND RECOVERY OF HYDROCARBONS FROM PARTICULATE MATTER | THE PENN STATE RESEARCH FOUNDATION (US) | 2014-02-27 | — | — | US | disclosed |
| US-8603327-B2 | Analogue ionic liquids for the separation and recovery of hydrocarbons from particulate matter | THE PENN STATE RESEARCH FOUNDATION (US) | 2013-12-10 | — | — | US | disclosed |
| EP-2578285-A1 | Analogue ionic liquids for the separation and recovery of hydrocarbons from particulate matter | The Penn State Research Foundation (US) | 2013-04-10 | — | — | EP | disclosed |
| CN-102718684-A | Synthetic method of hyamine modified acrylate antistatic agent | TAICANG XINXING LIGHT INDUSTRY AUX IES FACTORY | 2012-10-10 | — | — | CN | disclosed |
| US-20120048783-A1 | ANALOGUE IONIC LIQUIDS FOR THE SEPARATION AND RECOVERY OF HYDROCARBONS FROM PARTICULATE MATTER | PENN STATE RESEARCH FOUNDATION (US) | 2012-03-01 | — | — | US | disclosed |
| EP-0258855-B1 | PROCESS FOR THE PREPARATION OF AMINOTHIOPHENE DERIVATIVES | BASF Aktiengesellschaft (DE) | 1992-02-12 | — | — | EP | disclosed |
| US-4814465-A | Preparation of aminothiophene derivatives | BASF AKTIENGESELLSCHAFT (DE) | 1989-03-21 | — | — | US | disclosed |
| EP-0258855-A2 | Process for the preparation of aminothiophene derivatives | BASF Aktiengesellschaft (DE) | 1988-03-09 | — | — | EP | disclosed |
| US-3944430-A | Rechargeable galvanic cell and electrolyte therefor-II | UNION CARBIDE CORPORATION (US) | 1976-03-16 | — | — | US | disclosed |