SCHEMBL715537

SCHEMBL715537

[c]1ccc(N(c2ccccc2)c2cccc3ccccc23)cc1

nearest known ligand 0.44

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 9/20 0.44
L3MBTL1 Q9Y468 1/20 0.36
CYP1A2 P05177 3/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP2C19 P33261 1/20 0.35
ALDH1A1 P00352 3/20 0.33
CYP2A6 P11509 3/20 0.33
TDP1 Q9NUW8 2/20 0.33
TSHR P16473 2/20 0.33
HSD17B10 Q99714 2/20 0.33
NR4A1 P22736 1/20 0.32
NR4A2 P43354 1/20 0.32
NR4A3 Q92570 1/20 0.32
HPGD P15428 1/20 0.32
KEAP1 Q14145 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16353898 0.93 SIGMAR1 (0.43) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6
Water SCHEMBL10786412 0.91 SIGMAR1 (0.50) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6
SCHEMBL272955 0.89 SIGMAR1 (0.51) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6
SCHEMBL29906514 0.89 SIGMAR1 (0.51) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6
SCHEMBL4893902 0.87 SIGMAR1 (0.50) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6
SCHEMBL2362015 0.87 SIGMAR1 (0.50) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6
SCHEMBL4580501 0.87 SIGMAR1 (0.50) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6
SCHEMBL17965662 0.85 SIGMAR1 (0.36) SIGMAR1CYP1A2CYP2D6ALDH1A1CYP2A6
SCHEMBL13020775 0.85 SIGMAR1 (0.49) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6
SCHEMBL13720498 0.85 SIGMAR1 (0.49) SIGMAR1L3MBTL1CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9112159-B2 Bipolar hosts for light emitting devices NITTO DENKO CORPORATION (JP) 2015-08-18 US claimed
WO-2014093361-A1 BIPOLAR HOSTS FOR LIGHT EMITTING DEVICES NITTO DENKO CORPORATION (JP) 2014-06-19 WO claimed
US-20140163237-A1 BIPOLAR HOSTS FOR LIGHT EMITTING DEVICES Nitto Denko Corportion (JP) 2014-06-12 US claimed
CN-101467280-B Light emitting devices and compositions NITTO DENKO CORP 2012-05-23 CN claimed
CN-101467280-A Light emitting devices and compositions NITTO DENKO CORP (JP) 2009-06-24 CN claimed
US-6838193-B2 Organic light-emitting diode ACADEMIA SINICA (TW) 2005-01-04 US claimed
US-20040234811-A1 Energy-transfer type light-emitting polymer based on poly(p-phenylene vinylene) and preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2004-11-25 US claimed
US-20030186082-A1 Organic light-emitting diode TRANSPACIFIC IP LTD. (TW) 2003-10-02 US claimed
CN-111315828-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-09-29 CN disclosed
CN-112154167-B Composition, cured product, optical filter, and method for producing cured product 株式会社艾迪科 2023-08-22 CN disclosed
WO-2022209892-A1 CHARGE-TRANSPORTING VARNISH 日産化学株式会社 2022-10-06 WO disclosed
CN-110494501-B Phthalocyanine compound and use thereof 山本化成株式会社 2022-04-19 CN disclosed
US-20210159421-A1 COMPOSITION FOR FORMING CHARGE-TRANSPORTING THIN FILM NISSAN CHEMICAL CORPORATION (JP) 2021-05-27 US disclosed
US-11015061-B2 Phthalocyanine-based compound and uses of same YAMAMOTO CHEMICALS, INC. (JP) 2021-05-25 US disclosed
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same SEMICONDUCTOR ENERGY LABORATORY CO., LTD. 2010-03-11 US disclosed
EP-1867080-A4 COMPOSITE MATERIAL, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LAB (JP) 2009-08-12 EP disclosed
US-20090072714-A1 Composite Material, Material for Light-Emitting Element, Light-Emitting Element, Light-Emitting Device and Electronic Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2009-03-19 US disclosed
EP-1867080-A1 COMPOSITE MATERIAL, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2007-12-19 EP disclosed
WO-2006101018-A1 COMPOSITE MATERIAL, MATERIAL FOR LIGHT-EMITTING ELEMENT, LIGHT-EMITTING ELEMENT, LIGHT-EMITTING DEVICE AND ELECTRONIC DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2006-09-28 WO disclosed
US-20040234811-A1 Energy-transfer type light-emitting polymer based on poly(p-phenylene vinylene) and preparation thereof CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCE (CN) 2004-11-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100060155-A1 Organic Semiconductor Material and Light-Emitting Element, Light-Emitting Device, Lighting System, and Electronic Device Using the Same OXA1L, BECN1, MAP1LC3A SIGMAR1 1853/4885L3MBTL1 2080/4885CYP1A2 928/4885
US-20030186082-A1 Organic light-emitting diode CRY1, IK, LIG3 SIGMAR1 1255/4885L3MBTL1 137/4885CYP1A2 141/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.